STAYING NATURALLY YOUNG IN THE LONG RUN: a continuous search for less invasive and optimized treatments

Ageing of the face is the consequence of a complex synergy between skin textural changes and loss of facial volume. The skin, the soft tissues (notably fat and muscles) and the structural support are individually affected by ageing. 1

The ever-growing desire to maintain a youthful appearance in the long run has recently led to new dermatological procedures for treatment of skin ageing: an emphasis on minimally invasive treatments and techniques was then born to treat volume loss, wrinkles and skin photodamage.2 But what do patients really seek to obtain from a rejuvenation program? They actually want to look young and as natural as possible, both short term and long term.

Volume loss and severe wrinkles have to be treated by different dynamic and innovative approaches (the fourth dimension of full facial treatment must take into account the dynamism of the face) and with constantly more advanced products giving a natural appearance when the face is moving.3,4

Skin quality is also to be taken into account early in life (30’s) if the patients want to look younger in the long run. Nowadays, a better knowledge of skin metabolism and architecture has revealed that the alterations of the dermal connective tissue correspond to an age-related loss of the extracellular matrix (ECM). This loss is highly responsible for the appearance of the wrinkles that led to the concept of skin rejuvenation and beauty booster.2,5,6 Treating the skin with products, usually containing hyaluronic acid (cross-linked or not), mixed or not with oligo-nutrients (amino acids, vitamins and minerals), enhances the biosynthetic capacity of fibroblasts. This induces the reconstruction of an optimal physiologic environment, the enhancement of cell activity and the synthesis of collagen, elastin and hyaluronic acid therefore reforming a “younger ECM”.2,6

Ultimately, this leads to a firmer skin which is more elastic, more hydrated and more radiant. 6-8 However, despite good results on skin quality with these products, usually fine wrinkles hardly disappear.

Recently, a case report analyzing the benefi cial effect of TEOSYAL® RHA 1 on facial rejuvenation and the correction of fi ne wrinkles was released.9 TEOSYAL® RHA 1 has proven spectacular results to treat fi ne lines. With its unique dynamic rheological properties (high stretch, low strength), this fi ller is able to perfectly adapt to facial dynamic in order to stay invisible during facial movements. These features make TEOSYAL® RHA 1 a product of choice for the correction of fine wrinkles as well as for a global skin revitalization and thus for a global and long-lasting facial rejuvenation.

1. Coleman SR et al. The anatomy of the aging face: volume loss and changes in a 3-dimensional topography. Aesthetic Surg J. 2006(Suppl): S4-9. 2. Sparavigna A et al. Antiaging, photoprotective, and brightening activity in bioretalization: a new solution for aging skin. Clinical, cosmetic and investigational dermatology. 2015; : 57-65. 3. Teosyal RHA. Data on fi le 4. Michaud T et al. Facial dynamics and emotional expressions in facial aging treatments. Journal of cosmetic Dermatology. 2015. 5. Bayspeyras M et al. Clinical and biometrological efficacy of a hyaluronic acid-based mesotherapy product: a randomized controlled study. Arch Dermatol Res. 2013; 305: 673-82. 6. Iorizzo M et al. Biorejuvenation: theory and practice. Clinics in Dermatology. 2008; 26: 177-81. 7. Study report. Teosyal®Puresense Redensity [I] versus placebo. Pr. Humbert. Dec 2014. 8. Study report Teosyal®Puresense Redensity [I]. Dr. Knoll, Dr. Vivier, Dr. Carre, Dr. Micheels. May 2013. 9. Sito G & Branciaccio G. A new dynamic hyaluronic acid for facial rejuvenation: our evaluation. Anti-Age Magazine. 2015; 20: 90-93.

Patrice Delobel, PhD

Medico-Marketing Director, TEOXANE Laboratories