Until recently, the correction of facial blemishes was limited to an action of filling, with no regard for anything else. Many doctors were unsatisfied by this approach, and therefore it appeared necessary to rethink new methods, more complete and synergistic strategies, in order to meet the needs both of doctors and patients.

The Dynamic Redensification
is a recent method to deal with the
signs of time.This is a combined anti- ageing strategy, in which the “dynamic” filler TEOSYAL® RHA 1, a hyaluronic acid structured to be particularly versatile
and easy to handle, is combined with the active ingredients and nutrients of the bio-revitalizing TEOSYAL® REDENSITY [I], which contains, in addition to the non-cross-linked hyaluronic acid, alpha-lipoic acid, N-acetyl-L-cysteine, glutathione and other essential elements to protect the skin and stimulate tissue regeneration.The synergy between the Dermo-Restructuring Complex of REDENSITY [I] and the new morphology of TEOSYAL® RHA 1 makes possible the creation of a large ”reserve of hydration” and allows the skin to assume a renewed texture, a greater elasticity, a new brightness.

This way, we achieve significant results on at least three fronts:

1- reversal of oxidative processes
and protection from external factors (photoageing strategy);

2- redensification and dermal-epidermal regeneration (chronoageing strategy);

3- line and wrinkle correction (reshaping). With the Dynamic Redensification Protocol each correction is made to give health to the skin and an aesthetic improvement: biological improvement and aesthetic improvement thus go hand-in-hand.

And there’s more. The REDENSITY [I]/ TEOSYAL® RHA 1 treatment protocol is flexible – almost customizable,
I would say – because it is modulated in relation to the different morphotypes. This possibility, which gives great value to the professionalism of the doctor and allows to achieve the highest patient satisfaction, makes me speak of a strategy for the future!

We know that skin ageing changes, generally, in relation to age and can
be considered as the sum of a share
of genetic ageing (chronoageing)
and of another part related, instead,
to the habits and the external stresses
to which everyone’s skin is subjected day after day (photoageing). However, chronoageing and photoageing aren’t always inseparable with age. As a general principle, in my daily work, I tend to separate patients into two broad categories:

  • men and pre-menopausal women;
  • women after menopause.

The second major distinction which should be adopted will depend upon morphotypes. Very young people with initial ageing (which is likely photo-ageing, 18-25 years) can be treated with bio-stimulation, through REDENSITY [I], or even just encouraging the use at home of appropriate cosmeceuticals for a proper prevention.

But if we go up to grade 1 (mild to moderate photo-ageing, 25-45 years old) or to grades 2 and 3 (advanced photo-ageing, 45-60 years old / severe photo-ageing, over 60 years old), a concerted action of wrinkle filling and crosslinked support will be required. Here is a first example of combined use of REDENSITY [I] and TEOSYAL® RHA 1, which clarifies the value of the Dynamic Redensification Protocol.

Furthermore the concept of “combined” and “customized” is not limited to this phase. Keeping in mind the patient I have in front of me, I evaluate in each case the opportunity, if not the necessity, of having recourse to other treatments, such as peeling or microdermabrasion which, in synergy with the dynamic redensification, allow to reach excellent results.

The skin redensification protocol is supported and completed by a daily beauty routine that pays close attention not only to the quality of cosmeceutical products but also to the quality of our lifestyle.

TEOSYAL® PureSense RHA 1 to 4, TEOSYAL® PureSense REDENSITY [I] are medical devices, class III, and are regulated health products bearing the CE marking (CE0086) under this regulation. TEOSYAL® PureSense REDENSITY [I] is a mesotherapy product.TEOSYAL® PEN is a motorized and cordless device for hyaluronic acid injections in order to correct wrinkles and depressions. Manufactured by Juvaplus SA. TEOSYAL® PEN (class IIa), is a regulated health product which bears, under this regulation, the CE mark (CE0434).
For more information about those products, please consult your doctor and product instructions for use.

Technical data and cases presented reflect the personal experience of the physician.TEOXANE Laboratories could not be held responsible for the effects of these fillers when used outside CE marking.


Surgeon, Modena, Italy

STAYING NATURALLY YOUNG IN THE LONG RUN: a continuous search for less invasive and optimized treatments

Ageing of the face is the consequence of a complex synergy between skin textural changes and loss of facial volume. The skin, the soft tissues (notably fat and muscles) and the structural support are individually affected by ageing. 1

The ever-growing desire to maintain a youthful appearance in the long run has recently led to new dermatological procedures for treatment of skin ageing: an emphasis on minimally invasive treatments and techniques was then born to treat volume loss, wrinkles and skin photodamage.2 But what do patients really seek to obtain from a rejuvenation program? They actually want to look young and as natural as possible, both short term and long term.

Volume loss and severe wrinkles have to be treated by different dynamic and innovative approaches (the fourth dimension of full facial treatment must take into account the dynamism of the face) and with constantly more advanced products giving a natural appearance when the face is moving.3,4

Skin quality is also to be taken into account early in life (30’s) if the patients want to look younger in the long run. Nowadays, a better knowledge of skin metabolism and architecture has revealed that the alterations of the dermal connective tissue correspond to an age-related loss of the extracellular matrix (ECM). This loss is highly responsible for the appearance of the wrinkles that led to the concept of skin rejuvenation and beauty booster.2,5,6 Treating the skin with products, usually containing hyaluronic acid (cross-linked or not), mixed or not with oligo-nutrients (amino acids, vitamins and minerals), enhances the biosynthetic capacity of fibroblasts. This induces the reconstruction of an optimal physiologic environment, the enhancement of cell activity and the synthesis of collagen, elastin and hyaluronic acid therefore reforming a “younger ECM”.2,6

Ultimately, this leads to a firmer skin which is more elastic, more hydrated and more radiant. 6-8 However, despite good results on skin quality with these products, usually fine wrinkles hardly disappear.

Recently, a case report analyzing the benefi cial effect of TEOSYAL® RHA 1 on facial rejuvenation and the correction of fi ne wrinkles was released.9 TEOSYAL® RHA 1 has proven spectacular results to treat fi ne lines. With its unique dynamic rheological properties (high stretch, low strength), this fi ller is able to perfectly adapt to facial dynamic in order to stay invisible during facial movements. These features make TEOSYAL® RHA 1 a product of choice for the correction of fine wrinkles as well as for a global skin revitalization and thus for a global and long-lasting facial rejuvenation.

1. Coleman SR et al. The anatomy of the aging face: volume loss and changes in a 3-dimensional topography. Aesthetic Surg J. 2006(Suppl): S4-9. 2. Sparavigna A et al. Antiaging, photoprotective, and brightening activity in bioretalization: a new solution for aging skin. Clinical, cosmetic and investigational dermatology. 2015; : 57-65. 3. Teosyal RHA. Data on fi le 4. Michaud T et al. Facial dynamics and emotional expressions in facial aging treatments. Journal of cosmetic Dermatology. 2015. 5. Bayspeyras M et al. Clinical and biometrological efficacy of a hyaluronic acid-based mesotherapy product: a randomized controlled study. Arch Dermatol Res. 2013; 305: 673-82. 6. Iorizzo M et al. Biorejuvenation: theory and practice. Clinics in Dermatology. 2008; 26: 177-81. 7. Study report. Teosyal®Puresense Redensity [I] versus placebo. Pr. Humbert. Dec 2014. 8. Study report Teosyal®Puresense Redensity [I]. Dr. Knoll, Dr. Vivier, Dr. Carre, Dr. Micheels. May 2013. 9. Sito G & Branciaccio G. A new dynamic hyaluronic acid for facial rejuvenation: our evaluation. Anti-Age Magazine. 2015; 20: 90-93.

Patrice Delobel, PhD

Medico-Marketing Director, TEOXANE Laboratories